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LASER FLARE PHOTOMETRY IN PRIMARY RHEGMATOGENOUS RETINAL DETACHMENT: An Evaluation of 2,487 Cases.
Gietzelt, Caroline; Hoerster, Robert; Schiller, Petra; Hermann, Saskia; Kraus, Daria; Holz, Frank G; Guthoff, Rainer; Agostini, Hansjürgen; Spitzer, Martin S; Wiedemann, Peter; Lommatzsch, Albrecht; Boden, Karl T; Bartz-Schmidt, Ulrich; Bemme, Sebastian; Tamm, Svenja; Maier, Mathias; Roider, Johann; Kirchhof, Bernd; Fauser, Sascha; Schaub, Friederike.
Affiliation
  • Gietzelt C; Department of Ophthalmology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • Hoerster R; MVZ Augenärztliches Diagnostik- und Therapiecentrum (ADTC) Mönchengladbach/Erkelenz GmbH, Erkelenz, Germany.
  • Schiller P; Faculty of Medicine, Institute of Medical Statistics and Computational Biology (IMSB), University of Cologne, Cologne, Germany.
  • Hermann S; Department of Ophthalmology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • Kraus D; Clinical Trials Center Cologne (CTCC), Cologne, Germany.
  • Holz FG; Department of Ophthalmology, University of Bonn, Bonn, Germany.
  • Guthoff R; Department of Ophthalmology, Faculty of Medicine, University of Düsseldorf, Düsseldorf, Germany.
  • Agostini H; Eye Center, Medical Faculty, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.
  • Spitzer MS; Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Wiedemann P; Department of Ophthalmology, University of Leipzig, Leipzig, Germany.
  • Lommatzsch A; Department of Ophthalmology, Franziskus Hospital, Münster, Germany.
  • Boden KT; Eye Clinic Sulzbach, Knappschaft Hospital Saar, Sulzbach, Germany.
  • Bartz-Schmidt U; Center of Ophthalmology, University Eye Hospital Tübingen, Tübingen, Germany.
  • Bemme S; Department of Ophthalmology, University Medical Center Göttingen, Göttingen, Germany.
  • Tamm S; Department of Ophthalmology, University of Regensburg, Regensburg, Germany.
  • Maier M; Department of Ophthalmology, Technical University Munich (TUM), Munich, Germany.
  • Roider J; Department of Ophthalmology, University of Kiel, Kiel, Germany.
  • Kirchhof B; Department of Ophthalmology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • Fauser S; F. Hofmann-La Roche AG, Basel, Switzerland; and.
  • Schaub F; Department of Ophthalmology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Retina ; 44(5): 764-773, 2024 05 01.
Article in En | MEDLINE | ID: mdl-38181515
ABSTRACT

PURPOSE:

Exploratory analysis associated with the prospective, multicenter, randomized PRIVENT trial. To characterize the associations between laser flare photometry and anatomical and epidemiological features of rhegmatogenous retinal detachment (RRD).

METHODS:

The authors measured laser flare values of all 3,048 prescreened patients excluding those with comorbidities. A mixed regression analysis evaluated the strength of the influencing factors like age, sex, lens status, and presence and extent of RRD on laser flare.

RESULTS:

Rhegmatogenous retinal detachment was more frequent in men (65.8%) than in women (34.2%, P < 0.001) and in right (52%) than in left eyes (48%, P = 0.045). Phakic RRD affected less quadrants and was less likely to be associated with macula-off status than pseudophakic RRD (48.4% vs. 58.0% macula off, 23% vs. 31% ≥3 quadrants, P < 0.001). Laser flare of affected eyes was significantly higher compared with fellow eyes (12.6 ± 15.2 vs. 8.3 ± 7.4 pc/ms, P < 0.001). The factors age, sex, lens status, presence of RRD, and the number of quadrants affected were independent influencing factors on laser flare. R 2 was 0.145 for phakic and 0.094 for pseudophakic eyes.

CONCLUSION:

The results indicate that there may be more factors affecting laser flare than previously assumed. This might limit flare as predictive value for PVR and retinal redetachment.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Photometry / Retinal Detachment Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Retina Year: 2024 Type: Article Affiliation country: Germany

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Photometry / Retinal Detachment Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Retina Year: 2024 Type: Article Affiliation country: Germany