Your browser doesn't support javascript.
loading
Incidence, risk factors and outcome of postoperative acute kidney injury in China.
Cheng, Yichun; Nie, Sheng; Zhao, Xingyang; Xu, Xin; Xu, Hong; Liu, Bicheng; Weng, Jianping; Chunbo, Chen; Liu, Huafeng; Yang, Qiongqiong; Li, Hua; Kong, Yaozhong; Li, Guisen; Wan, Qijun; Zha, Yan; Hu, Ying; Shi, Yongjun; Zhou, Yilun; Su, Guobin; Tang, Ying; Gong, Mengchun; Hou, Fan Fan; Ge, Shuwang; Xu, Gang.
Affiliation
  • Cheng Y; Department of Nephrology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology.
  • Nie S; Division of Nephrology, Nanfang Hospital, Southern Medical University; National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Guangdong Provincial Institute of Nephrology, Guangdong Provincial Key Laboratory of Renal Failure Research.
  • Zhao X; Department of Nephrology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology.
  • Xu X; Division of Nephrology, Nanfang Hospital, Southern Medical University; National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Guangdong Provincial Institute of Nephrology, Guangdong Provincial Key Laboratory of Renal Failure Research.
  • Xu H; Children's Hospital of Fudan University.
  • Liu B; Institute of Nephrology, Zhongda Hospital, Southeast University School of Medicine.
  • Weng J; Department of Endocrinology, First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China.
  • Chunbo C; Department of Critical Care Medicine, Maoming People's Hospital, Maoming.
  • Liu H; Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University.
  • Yang Q; Department of Nephrology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University.
  • Li H; Sir Run Run Shaw Hospital, Zhejiang University School of Medicine.
  • Kong Y; Department of Nephrology, First People's Hospital of Foshan.
  • Li G; Renal Department and Institute of Nephrology, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Sichuan Clinical Research Center for Kidney Diseases.
  • Wan Q; Second People's Hospital of Shenzhen, Shenzhen University.
  • Zha Y; Guizhou Provincial People's Hospital, Guizhou University.
  • Hu Y; Second Affiliated Hospital of Zhejiang University School of Medicine.
  • Shi Y; Huizhou Municipal Central Hospital, Sun Yat-Sen University.
  • Zhou Y; Department of Nephrology, Beijing Tiantan Hospital, Capital Medical University.
  • Su G; Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, Second Affiliated Hospital, Second Clinical College, Guangzhou University of Chinese Medicine.
  • Tang Y; Third Affiliated Hospital of Southern Medical University.
  • Gong M; Institute of Health Management, Southern Medical University, DHC Technologies.
  • Hou FF; DHC Technologies, Beijing, China.
  • Ge S; Division of Nephrology, Nanfang Hospital, Southern Medical University; National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Guangdong Provincial Institute of Nephrology, Guangdong Provincial Key Laboratory of Renal Failure Research.
  • Xu G; Department of Nephrology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology.
Nephrol Dial Transplant ; 39(6): 967-977, 2024 May 31.
Article in En | MEDLINE | ID: mdl-38262746
ABSTRACT

BACKGROUND:

Postoperative acute kidney injury (AKI) is a common condition after surgery, however, the available data about nationwide epidemiology of postoperative AKI in China from large and high-quality studies are limited. This study aimed to determine the incidence, risk factors and outcomes of postoperative AKI among patients undergoing surgery in China.

METHODS:

This was a large, multicentre, retrospective study performed in 16 tertiary medical centres in China. Adult patients (≥18 years of age) who underwent surgical procedures from 1 January 2013 to 31 December 2019 were included. Postoperative AKI was defined by the Kidney Disease Improving Global Outcomes creatinine criteria. The associations of AKI and in-hospital outcomes were investigated using logistic regression models adjusted for potential confounders.

RESULTS:

Among 520 707 patients included in our study, 25 830 (5.0%) patients developed postoperative AKI. The incidence of postoperative AKI varied by surgery type, which was highest in cardiac (34.6%), urologic (8.7%) and general (4.2%) surgeries. A total of 89.2% of postoperative AKI cases were detected in the first 2 postoperative days. However, only 584 (2.3%) patients with postoperative AKI were diagnosed with AKI on discharge. Risk factors for postoperative AKI included older age, male sex, lower baseline kidney function, pre-surgery hospital stay ≤3 days or >7 days, hypertension, diabetes mellitus and use of proton pump inhibitors or diuretics. The risk of in-hospital death increased with the stage of AKI. In addition, patients with postoperative AKI had longer lengths of hospital stay (12 versus 19 days) and were more likely to require intensive care unit care (13.1% versus 45.0%) and renal replacement therapy (0.4% versus 7.7%).

CONCLUSIONS:

Postoperative AKI was common across surgery type in China, particularly for patients undergoing cardiac surgery. Implementation and evaluation of an alarm system is important for the battle against postoperative AKI.
Subject(s)
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Postoperative Complications / Acute Kidney Injury Type of study: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Nephrol Dial Transplant Journal subject: NEFROLOGIA / TRANSPLANTE Year: 2024 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Postoperative Complications / Acute Kidney Injury Type of study: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Nephrol Dial Transplant Journal subject: NEFROLOGIA / TRANSPLANTE Year: 2024 Type: Article