The inhibition of several components of terminal complement pathway results in C3 binding to PNH red blood cells.
Am J Hematol
; 99(3): 505-507, 2024 03.
Article
in En
| MEDLINE
| ID: mdl-38264841
ABSTRACT
C3 binding on PNH red blood cells after in vitro complement activation in normal and terminal complement depleted (∆5, ∆6, ∆9) sera C3 binding, and the subsequent extravascular hemolysis, happens anytime there is a block of a component of the terminal complement pathway.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Hemoglobinuria, Paroxysmal
Limits:
Humans
Language:
En
Journal:
Am J Hematol
Year:
2024
Type:
Article
Affiliation country:
Italy