Supplemental Patch Testing Identifies Allergens Missed by Standard Screening Series.
Dermatitis
; 35(4): 366-372, 2024.
Article
in En
| MEDLINE
| ID: mdl-38285482
ABSTRACT
Background:
Supplemental patch testing is an adjunct to standard patch test screening series.Objective:
To determine the demographics, characteristics, frequency, relevance, and interpretation of patch test reactions for supplemental patch testing.Methods:
Retrospective study of patients tested 2017-2020 with North American Contact Dermatitis Group (NACDG) and supplemental screening series (Supplemental Series A [SSA], Supplemental Series B [SSB]). Demographics, characteristics, reaction strengths, relevance, and final interpretation were recorded.Results:
Cohort included 791 patients; 73.5% female, 68.6% age >40 years. 74.1% were White, 15.2% Black, 5.7% Asian, and 1.5% Hispanic. The most common Dermatitis sites were scattered/generalized (27.2%), face (24.0%), and hands (23.5%). For 2017-2018 and 2019-2020, respectively, 82% (318/388) and 78.4% (316/403) had ≥1 "allergic" reaction. In addition, 13.5% (52/385) and 11.7% (47/403) had SSA reactions, and 38.1% (115/302) and 31.5% (101/321) had SSB reactions. In the 87 (2017-2018) and 99 (2019-2020) patients with negative NACDG testing, 17 (19.5%) and 12 (12.1%) had supplemental reactions. Of the 34 supplemental allergens with reaction frequency ≥1%, 58.8% (20/34) are not part of the American Contact Dermatitis Society 90 (2020) or NACDG 2021-2022 screening series. The highest frequency allergens from this group were dodecyl and octyl gallate, cinnamic alcohol, phenyl salicylate, hexahydro-1,3,5-tris-(2-hydroxyethyl) triazine, and abitol.Conclusions:
Supplemental patch testing identifies additional relevant allergens in patients with suspected allergic contact Dermatitis.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Patch Tests
/
Allergens
/
Dermatitis, Allergic Contact
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Screening_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Dermatitis
Journal subject:
DERMATOLOGIA
Year:
2024
Type:
Article
Affiliation country:
United States