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Paeoniflorin alleviated muscle atrophy in cancer cachexia through inhibiting TLR4/NF-κB signaling and activating AKT/mTOR signaling.
Zhu, Zixia; Li, Cong; Gu, Xiaofan; Wang, Xiaoting; Zhang, Gang; Fan, Meng; Zhao, Yun; Liu, Xuan; Zhang, Xiongwen.
Affiliation
  • Zhu Z; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, PR China.
  • Li C; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, PR China.
  • Gu X; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, PR China.
  • Wang X; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, PR China.
  • Zhang G; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, PR China.
  • Fan M; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, PR China.
  • Zhao Y; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, PR China.
  • Liu X; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201003, China. Electronic address: xuanliu@shutcm.edu.cn.
  • Zhang X; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, PR China. Electronic address: xwzhang@sat.ecnu.edu.cn.
Toxicol Appl Pharmacol ; 484: 116846, 2024 Mar.
Article in En | MEDLINE | ID: mdl-38331105
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Monoterpenes / Glucosides / Neoplasms Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 2024 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Monoterpenes / Glucosides / Neoplasms Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 2024 Type: Article