Risk-based approach of bioanalytical methods for clinical immunogenicity assessment of multidomain biotherapeutics.

Mao, Yan; Coble, Kelly

Mao, Yan; Coble, Kelly.

Affiliation

Mao Y; Bioanalytical Sciences, Drug Metabolism & Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA.
Coble K; Bioanalytical Sciences, Drug Metabolism & Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA.

Bioanalysis ; 16(5): 271-275, 2024 Mar.

Article in En | MEDLINE | ID: mdl-38334126

ABSTRACT

ABSTRACT

Tweetable abstract Risk-based bioanalytical method development for clinical antidrug antibody detection and characterization of multidomain biotherapeutics.

Key words

bispecific biotherapeutics; clinical antidrug antibody characterization; multidomain biotherapeutics; pre-existing antidrug antibody; treatment-emergent antidrug antibody

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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Etiology_studies / Risk_factors_studies Language: En Journal: Bioanal. (Online) / Bioanalysis / Bioanalysis (Online) Year: 2024 Type: Article Affiliation country: United States

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