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SLC25A39 links mitochondrial GSH sensing with iron metabolism.
Chen, Xiong; Gan, Boyi.
Affiliation
  • Chen X; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Gan B; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; The University of Texas MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA. Electronic address: bgan@mdanderson.org.
Mol Cell ; 84(4): 616-618, 2024 Feb 15.
Article in En | MEDLINE | ID: mdl-38364779
ABSTRACT
Two recent studies by Liu et al.1 in Science and Shi et al.2 in this issue of Molecular Cell identify a mitochondrial GSH-sensing mechanism that couples SLC25A39-mediated GSH import to iron metabolism, advancing our understanding of nutrient sensing within organelles.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mitochondrial Membrane Transport Proteins / Iron / Mitochondria Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2024 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mitochondrial Membrane Transport Proteins / Iron / Mitochondria Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2024 Type: Article Affiliation country: United States