Section E6.7-6.12 of the American College of Medical Genetics and Genomics (ACMG) Technical Laboratory Standards: Cytogenomic studies of acquired chromosomal abnormalities in solid tumors.
Genet Med
; 26(4): 101070, 2024 04.
Article
in En
| MEDLINE
| ID: mdl-38376505
ABSTRACT
Clinical cytogenomic studies of solid tumor samples are critical to the diagnosis, prognostication, and treatment selection for cancer patients. An overview of current cytogenomic techniques for solid tumor analysis is provided, including standards for sample preparation, clinical and technical considerations, and documentation of results. With the evolving technologies and their application in solid tumor analysis, these standards now include sequencing technology and optical genome mapping, in addition to the conventional cytogenomic methods, such as G-banded chromosome analysis, fluorescence in situ hybridization, and chromosomal microarray analysis. This updated Section E6.7-6.12 supersedes the previous Section E6.5-6.8 in Section E Clinical Cytogenetics of the American College of Medical Genetics and Genomics Standards for Clinical Genetics Laboratories.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Genetics, Medical
/
Neoplasms
Limits:
Humans
Country/Region as subject:
America do norte
Language:
En
Journal:
Genet Med
Journal subject:
GENETICA MEDICA
Year:
2024
Type:
Article