Influenza vaccine effectiveness against hospitalizations associated with influenza A(H3N2) in Hong Kong children aged 9 months to 17 years, June-November 2023.
Vaccine
; 42(8): 1878-1882, 2024 Mar 19.
Article
in En
| MEDLINE
| ID: mdl-38395722
ABSTRACT
A test negative study was carried out from 13 June through to 15 November 2023 enrolling 3183 children hospitalized with acute respiratory illness in Hong Kong. Influenza A and B viruses were detected in 528 (16.6%) children, among which 419 (79.4%) were influenza A(H3N2). The overall vaccine effectiveness against hospitalization associated with any influenza virus infection was estimated as 22.4% (95% CI -11.7%, 46.1%), and against influenza A(H3N2) specifically was 14.3% (95% CI -29.2%, 43.2%). Despite the moderate to low VE estimated here, which could be a result of waning immunity and antigenic drift, influenza vaccination remains an important approach to reduce the impact of influenza in children.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Influenza Vaccines
/
Influenza, Human
Limits:
Child
/
Humans
Country/Region as subject:
Asia
Language:
En
Journal:
Vaccine
Year:
2024
Type:
Article
Affiliation country:
China