Isolation, structural elucidation, and chemical synthesis of 2-hydroxy-3-octadecyl-5-methoxy-1,4-benzoquinone (irisoquin), a cytotoxic constituent of Iris missouriensis.

Wong, S M; Pezzuto, J M; Fong, H H; Farnsworth, N R

Wong, S M; Pezzuto, J M; Fong, H H; Farnsworth, N R.

J Pharm Sci ; 74(10): 1114-6, 1985 Oct.

Article in En | MEDLINE | ID: mdl-3841153

Subject(s)

Antineoplastic Agents, Phytogenic/analysis; Benzoquinones; Plants, Medicinal/analysis; Quinones/analysis; Animals; Antineoplastic Agents, Phytogenic/chemical synthesis; Antineoplastic Agents, Phytogenic/pharmacology; Cell Line; Chemical Phenomena; Chemistry; Humans; KB Cells/pathology; Leukemia P388/pathology; Mice; Quinones/chemical synthesis; Quinones/pharmacology; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Plants, Medicinal / Quinones / Benzoquinones / Antineoplastic Agents, Phytogenic Limits: Animals / Humans Language: En Journal: J Pharm Sci Year: 1985 Type: Article

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