Advances in sepsis biomarkers.
Adv Clin Chem
; 119: 117-166, 2024.
Article
in En
| MEDLINE
| ID: mdl-38514209
ABSTRACT
Sepsis, a dysregulated host immune response to an infectious agent, significantly increases morbidity and mortality for hospitalized patients worldwide. This chapter reviews (1) the basic principles of infectious diseases, pathophysiology and current definition of sepsis, (2) established sepsis biomarkers such lactate, procalcitonin and C-reactive protein, (3) novel, newly regulatory-cleared/approved biomarkers, such as assays that evaluate white blood cell properties and immune response molecules, and (4) emerging biomarkers and biomarker panels to highlight future directions and opportunities in the diagnosis and management of sepsis.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sepsis
Limits:
Humans
Language:
En
Journal:
Adv Clin Chem
/
Adv. clin. chem
/
Advances in clinical chemistry
Year:
2024
Type:
Article
Affiliation country:
United States