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Trauma diagnostic-related target proteins and their detection techniques.
Wei, YiLiu; Ren, Xiaohan; Yuan, Zhitao; Hong, Jie; Wang, Tao; Chen, Weizhi; Xu, Yuqing; Ding, Jinwang; Lin, Jun; Jiang, Wenqian; Zhang, Peng; Wu, Qiaoyi.
Affiliation
  • Wei Y; Department of Trauma Center & Emergency Surgery, The First Affiliated Hospital of Fujian Medical University, 350004 Fuzhou, China.
  • Ren X; Department of Trauma Center and Emergency Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, 350004 Fuzhou, China.
  • Yuan Z; Institute of Applied Genomics, Fuzhou University, No. 2 Xueyuan Road, 350108 Fuzhou, China.
  • Hong J; College of Biological Science and Engineering, Fuzhou University, No. 2 Xueyuan Road, 350108 Fuzhou, China.
  • Wang T; Institute of Applied Genomics, Fuzhou University, No. 2 Xueyuan Road, 350108 Fuzhou, China.
  • Chen W; College of Biological Science and Engineering, Fuzhou University, No. 2 Xueyuan Road, 350108 Fuzhou, China.
  • Xu Y; Department of Trauma Center & Emergency Surgery, The First Affiliated Hospital of Fujian Medical University, 350004 Fuzhou, China.
  • Ding J; Department of Trauma Center and Emergency Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, 350004 Fuzhou, China.
  • Lin J; Institute of Applied Genomics, Fuzhou University, No. 2 Xueyuan Road, 350108 Fuzhou, China.
  • Jiang W; College of Biological Science and Engineering, Fuzhou University, No. 2 Xueyuan Road, 350108 Fuzhou, China.
  • Zhang P; Department of Trauma Center & Emergency Surgery, The First Affiliated Hospital of Fujian Medical University, 350004 Fuzhou, China.
  • Wu Q; Department of Trauma Center and Emergency Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, 350004 Fuzhou, China.
Expert Rev Mol Med ; 26: e7, 2024 Apr 11.
Article in En | MEDLINE | ID: mdl-38602081
ABSTRACT
Trauma is a significant health issue that not only leads to immediate death in many cases but also causes severe complications, such as sepsis, thrombosis, haemorrhage, acute respiratory distress syndrome and traumatic brain injury, among trauma patients. Target protein identification technology is a vital technique in the field of biomedical research, enabling the study of biomolecular interactions, drug discovery and disease treatment. It plays a crucial role in identifying key protein targets associated with specific diseases or biological processes, facilitating further research, drug design and the development of treatment strategies. The application of target protein technology in biomarker detection enables the timely identification of newly emerging infections and complications in trauma patients, facilitating expeditious medical interventions and leading to reduced post-trauma mortality rates and improved patient prognoses. This review provides an overview of the current applications of target protein identification technology in trauma-related complications and provides a brief overview of the current target protein identification technology, with the aim of reducing post-trauma mortality, improving diagnostic efficiency and prognostic outcomes for patients.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Injuries, Traumatic Limits: Humans Language: En Journal: Expert Rev Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2024 Type: Article Affiliation country: China

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Injuries, Traumatic Limits: Humans Language: En Journal: Expert Rev Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2024 Type: Article Affiliation country: China