Triplet-Triplet Annihilation Upconversion-Based Photolysis: Applications in Photopharmacology.
Adv Healthc Mater
; 13(19): e2400354, 2024 Jul.
Article
in En
| MEDLINE
| ID: mdl-38613491
ABSTRACT
The emerging field of photopharmacology is a promising chemobiological methodology for optical control of drug activities that could ultimately solve the off-target toxicity outside the disease location of many drugs for the treatment of a given pathology. The use of photolytic reactions looks very attractive for a light-activated drug release but requires to develop photolytic reactions sensitive to red or near-infrared light excitation for better tissue penetration. This review will present the concepts of triplet-triplet annihilation upconversion-based photolysis and their recent in vivo applications for light-induced drug delivery using photoactivatable nanoparticles.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Photolysis
Limits:
Animals
/
Humans
Language:
En
Journal:
Adv Healthc Mater
Year:
2024
Type:
Article
Affiliation country:
France