Are novel or locally adapted pathogens more devastating and why? Resolving opposing hypotheses.
Ecol Lett
; 27(5): e14431, 2024 May.
Article
in En
| MEDLINE
| ID: mdl-38712705
ABSTRACT
There is a rich literature highlighting that pathogens are generally better adapted to infect local than novel hosts, and a separate seemingly contradictory literature indicating that novel pathogens pose the greatest threat to biodiversity and public health. Here, using Batrachochytrium dendrobatidis, the fungus associated with worldwide amphibian declines, we test the hypothesis that there is enough variance in "novel" (quantified by geographic and phylogenetic distance) host-pathogen outcomes to pose substantial risk of pathogen introductions despite local adaptation being common. Our continental-scale common garden experiment and global-scale meta-analysis demonstrate that local amphibian-fungal interactions result in higher pathogen prevalence, pathogen growth, and host mortality, but novel interactions led to variable consequences with especially virulent host-pathogen combinations still occurring. Thus, while most pathogen introductions are benign, enough variance exists in novel host-pathogen outcomes that moving organisms around the planet greatly increases the chance of pathogen introductions causing profound harm.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Host-Pathogen Interactions
/
Batrachochytrium
Limits:
Animals
Language:
En
Journal:
Ecol Lett
Year:
2024
Type:
Article
Affiliation country:
United States