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Improving the in vivo QTc assay: Nonclinical concentration-QTc modeling for risk assessment.
Wisialowski, Todd A; Ether, Nick; Foley, C Michael; Kleiman, Robert; Koshman, Yevgeniya; Leishman, Derek; Martel, Eric; Nichols, Jill V; Popp, Julia; Rajamani, Sridharan; Riley, Steve; Rossman, Eric I; Vargas, Hugo M.
Affiliation
  • Wisialowski TA; Pfizer, Groton, CT, USA. Electronic address: todd.a.wisialowski@pfizer.com.
  • Ether N; Amgen Inc., Thousand Oaks, CA, USA.
  • Foley CM; AbbVie, North Chicago, IL, USA.
  • Kleiman R; Clario, Philadelphia, PA, USA.
  • Koshman Y; AbbVie, North Chicago, IL, USA.
  • Leishman D; Eli Lilly and Company, Indianapolis, IN, USA.
  • Martel E; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.
  • Nichols JV; Labcorp, Madison, WI, USA.
  • Popp J; Labcorp, Madison, WI, USA.
  • Rajamani S; Johnson & Johnson Innovative Medicine, CA, USA.
  • Riley S; Pfizer, Groton, CT, USA.
  • Rossman EI; GSK, Collegeville, PA, USA.
  • Vargas HM; Amgen Inc., Thousand Oaks, CA, USA.
J Pharmacol Toxicol Methods ; 128: 107515, 2024.
Article in En | MEDLINE | ID: mdl-38777240
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Electrocardiography Limits: Animals / Humans Language: En Journal: J Pharmacol Toxicol Methods Journal subject: FARMACOLOGIA / TOXICOLOGIA Year: 2024 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Electrocardiography Limits: Animals / Humans Language: En Journal: J Pharmacol Toxicol Methods Journal subject: FARMACOLOGIA / TOXICOLOGIA Year: 2024 Type: Article