[Diagnostics and treatment challenges and research progress in early-onset gastric cancer].
Zhonghua Wei Chang Wai Ke Za Zhi
; 27(5): 436-440, 2024 May 25.
Article
in Zh
| MEDLINE
| ID: mdl-38778681
ABSTRACT
The incidence of gastric cancer has decreased, while the occurrence of early-onset gastric cancer has increased. There is no consensus on the definition of early-onset gastric cancer currently. The characteristics of tumor staging and differentiation, coupled with the lack of targeted comprehensive treatment, present a significant clinical challenge in managing early-onset gastric cancer. Relevant studies have analyzed the genetic characteristics of early-onset gastric cancer and have preliminarily revealed its relationship with Helicobacter pylori infection and molecular subtypes. These findings have the potential to contribute to the prevention and personalized treatment of early-onset gastric cancer. In the future, larger-scale evidence-based data are needed to establish diagnostic criteria, elucidate the mechanisms, and develop targeted diagnostic and therapeutic strategies of early-onset gastric cancer.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Stomach Neoplasms
/
Helicobacter pylori
/
Helicobacter Infections
Limits:
Humans
Language:
Zh
Journal:
Zhonghua Wei Chang Wai Ke Za Zhi
Journal subject:
GASTROENTEROLOGIA
Year:
2024
Type:
Article
Affiliation country:
China