Giant retroperitoneal liposarcoma with multiple organ involvement: a case report and literature review.
BMC Nephrol
; 25(1): 281, 2024 Aug 29.
Article
in En
| MEDLINE
| ID: mdl-39210338
ABSTRACT
BACKGROUND:
Retroperitoneal liposarcoma (RPLPS) is a relatively rare disease. Liposarcomas vary in size, but sizeable RPLPS larger than 30 cm in diameter are very rare, and their diagnosis and treatment present significant challenges. CASE PRESENTATION We report a 58-year-old male patient who was admitted to the hospital with an increased abdominal circumference and was later diagnosed with a giant RPLPS. The liposarcoma was found to adhere to the right kidney and the entire ureter, invading the ascending colon. The patient underwent complete combined surgical resection. The tumor was removed intact, measured 55.0 cm × 30.0 cm × 18.0 cm, and weighed 19.8 kg. Histopathologic analysis revealed well-differentiated liposarcoma (WDLPS). The patient was successfully discharged from the hospital and followed up for 6 months with no signs of recurrence.CONCLUSION:
RPLPS is a rare tumor with atypical clinical presentation. Surgery remains the most effective method of treatment for retroperitoneal sarcomas, with complete removal if there is local invasion. Preoperative examination, including three-dimensional (3D) reconstruction, is essential for surgical success. The role of adjuvant radiotherapy or chemotherapy remains controversial. However, clinicians should not rule them out as viable options.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Retroperitoneal Neoplasms
/
Liposarcoma
Limits:
Humans
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Male
/
Middle aged
Language:
En
Journal:
BMC Nephrol
Journal subject:
NEFROLOGIA
Year:
2024
Type:
Article
Affiliation country:
China