Degradation of fluorescent and radiolabelled sphingomyelins in intact cells by a non-lysosomal pathway.

Levade, T; Vidal, F; Vermeersch, S; Andrieu, N; Gatt, S; Salvayre, R

Levade, T; Vidal, F; Vermeersch, S; Andrieu, N; Gatt, S; Salvayre, R.

Affiliation

Levade T; Laboratoire de Biochimie, CJF INSERM 9206, Institut Louis Bugnard, C.H.U. Rangueil, Toulouse, France.

Biochim Biophys Acta ; 1258(3): 277-87, 1995 Oct 05.

Article in En | MEDLINE | ID: mdl-7548198

Subject(s)

Sphingomyelin Phosphodiesterase/metabolism; Sphingomyelins/metabolism; Bridged-Ring Compounds/pharmacology; Cell Line; Chloroquine/pharmacology; Dithiothreitol/pharmacology; Edetic Acid/pharmacology; Endocytosis; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Hydrolysis; Lysosomes/enzymology; Lysosomes/metabolism; Magnesium/metabolism; Magnesium/pharmacology; Niemann-Pick Diseases/metabolism; Norbornanes; Phosphodiesterase Inhibitors/pharmacology; Sphingomyelin Phosphodiesterase/antagonists & inhibitors; Thiocarbamates; Thiones/pharmacology; Tumor Cells, Cultured; Zinc/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Sphingomyelin Phosphodiesterase / Sphingomyelins Limits: Humans Language: En Journal: Biochim Biophys Acta Year: 1995 Type: Article Affiliation country: France

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