Synthesis and biological evaluation of cholecystokinin analogs in which the Asp-Phe-NH2 moiety has been replaced by a 3-amino-7-phenylheptanoic acid or a 3-amino-6-(phenyloxy)hexanoic acid.

Amblard, M; Rodriguez, M; Lignon, M F; Galas, M C; Bernad, N; Artis-Noël, A M; Hauad, L; Laur, J; Califano, J C; Aumelas, A

Amblard, M; Rodriguez, M; Lignon, M F; Galas, M C; Bernad, N; Artis-Noël, A M; Hauad, L; Laur, J; Califano, J C; Aumelas, A.

Affiliation

Amblard M; EP CNRS 51, Faculté de Pharmacie, Montpellier, France.

J Med Chem ; 36(20): 3021-8, 1993 Oct 01.

Article in En | MEDLINE | ID: mdl-7692048

Subject(s)

Caproates/chemistry; Cholecystokinin/analogs & derivatives; Heptanoic Acids/chemistry; Amino Acid Sequence; Amylases/metabolism; Animals; Binding Sites; Brain/metabolism; Cell Membrane/metabolism; Guinea Pigs; Magnetic Resonance Spectroscopy; Male; Molecular Sequence Data; Molecular Structure; Pancreas/drug effects; Pancreas/metabolism; Rats; Receptors, Cholecystokinin/metabolism; Sincalide/analogs & derivatives; Sincalide/chemistry; Sincalide/metabolism; Sincalide/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Cholecystokinin / Caproates / Heptanoic Acids Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 1993 Type: Article Affiliation country: France

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