Transfection of the c-myc oncogene into normal Epstein-Barr virus-harboring B cells results in new phenotypic and functional features resembling those of Burkitt lymphoma cells and normal centroblasts.

Cutrona, G; Ulivi, M; Fais, F; Roncella, S; Ferrarini, M

Cutrona, G; Ulivi, M; Fais, F; Roncella, S; Ferrarini, M.

Affiliation

Cutrona G; Istituto Nazionale per la Ricerca sul Cancro, IST, Genoa, Italy.

J Exp Med ; 181(2): 699-711, 1995 Feb 01.

Article in En | MEDLINE | ID: mdl-7836923

Subject(s)

Antigens, CD; B-Lymphocytes/virology; Burkitt Lymphoma/pathology; Genes, myc; Herpesvirus 4, Human; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, Differentiation/genetics; Apoptosis/genetics; B-Lymphocytes/pathology; Base Sequence; Burkitt Lymphoma/genetics; Burkitt Lymphoma/immunology; Cell Differentiation; DNA Primers; Down-Regulation; Herpesvirus 4, Human/isolation & purification; Humans; Membrane Glycoproteins; Molecular Sequence Data; Neprilysin/genetics; Phenotype; Proto-Oncogene Proteins/genetics; Proto-Oncogene Proteins c-bcl-2; Transfection; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / Antigens, CD / Genes, myc / Burkitt Lymphoma / Herpesvirus 4, Human Limits: Humans Language: En Journal: J Exp Med Year: 1995 Type: Article Affiliation country: Italy

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