Novel bishydroxamic acids as 5-lipoxygenase inhibitors.

Ohemeng, K A; Nguyen, V N; Schwender, C F; Singer, M; Steber, M; Ansell, J; Hageman, W

Ohemeng, K A; Nguyen, V N; Schwender, C F; Singer, M; Steber, M; Ansell, J; Hageman, W.

Affiliation

Ohemeng KA; R. W. Johnson Pharmaceutical Research Institute, Raritan, NJ 08869.

Bioorg Med Chem ; 2(3): 187-93, 1994 Mar.

Article in En | MEDLINE | ID: mdl-7922131

Subject(s)

Hydroxamic Acids/pharmacology; Lipoxygenase Inhibitors; Animals; Drug Design; Hydroxamic Acids/chemical synthesis; Hydroxamic Acids/chemistry; In Vitro Techniques; Leukotriene C4/antagonists & inhibitors; Masoprocol/analogs & derivatives; Masoprocol/chemistry; Masoprocol/pharmacology; Mice; Peritonitis/prevention & control; Rats; Structure-Activity Relationship; Tumor Cells, Cultured/enzymology

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Collection: 01-internacional Database: MEDLINE Main subject: Lipoxygenase Inhibitors / Hydroxamic Acids Limits: Animals Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 1994 Type: Article

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