[Effect of anti-aging drug on the activity of DNA methylase in rat liver].
Zhongguo Zhong Xi Yi Jie He Za Zhi
; 14(6): 354-6, 325-6, 1994 Jun.
Article
in Zh
| MEDLINE
| ID: mdl-8000226
ABSTRACT
An obvious anti-aging effect was found by Bushen Shengxue drug to treat Wistar rats. Using a method about incorporation of 3H-labeled methyl group of S-adenosyl-methionine (SAM) into DNA bases, the DNA methylase activity was assayed. The specific activity of DNA methylase was increased by treatment of this drug. The chromatographic behaviour of DNA methylase from rat liver was also changed. These results showed that the mechanism of anti-aging effect of this drug is probably related to DNA methylation.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Aging
/
Drugs, Chinese Herbal
/
DNA Modification Methylases
/
Liver
Limits:
Animals
Language:
Zh
Journal:
Zhongguo Zhong Xi Yi Jie He Za Zhi
Journal subject:
TERAPIAS COMPLEMENTARES
Year:
1994
Type:
Article