A genetic linkage map of the mouse: current applications and future prospects.

Copeland, N G; Jenkins, N A; Gilbert, D J; Eppig, J T; Maltais, L J; Miller, J C; Dietrich, W F; Weaver, A; Lincoln, S E; Steen, R G

Copeland, N G; Jenkins, N A; Gilbert, D J; Eppig, J T; Maltais, L J; Miller, J C; Dietrich, W F; Weaver, A; Lincoln, S E; Steen, R G.

Affiliation

Copeland NG; ABL-Basic Research Program, National Cancer Institute-Frederick Cancer Research and Development Center, MD 21702.

Science ; 262(5130): 57-66, 1993 Oct 01.

Article in En | MEDLINE | ID: mdl-8211130

ABSTRACT

ABSTRACT

Technological advances have made possible the development of high-resolution genetic linkage maps for the mouse. These maps in turn offer exciting prospects for understanding mammalian genome evolution through comparative mapping, for developing mouse models of human disease, and for identifying the function of all genes in the organism.

Subject(s)

Chromosome Mapping; Genome; Mice/genetics; Muridae/genetics; Animals; Biological Evolution; Cloning, Molecular; Crosses, Genetic; Female; Genetic Markers; Human Genome Project; Humans; Male; Multigene Family; Mutation; Neoplasms/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Chromosome Mapping / Genome / Mice / Muridae Limits: Animals / Female / Humans / Male Language: En Journal: Science Year: 1993 Type: Article

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