[Non-hysteroscopic thermodestruction of the endometrium using radio waves in the treatment of menorrhagia]. / Niet-hysteroscopische thermodestructie van het endometrium door radiogolven ter behandeling van menorragie.
Ned Tijdschr Geneeskd
; 137(35): 1776-80, 1993 Aug 28.
Article
in Nl
| MEDLINE
| ID: mdl-8371823
ABSTRACT
OBJECTIVE:
To test non-hysteroscopic thermodestruction of the endometrium for safety and efficiency.DESIGN:
Prospective pilot study from February 1991 to July 1992.SETTING:
University Hospital Nijmegen. PATIENTS ANDMETHOD:
There were 68 patients aged 30-55 years with menorrhagia, who did not want children but wished to retain the uterus. There were two patients with a subserous myoma but with a normal uterine cavity. Patients with hypergonadotropism, a markedly enlarged uterus, abnormalities at cytological examination of the cervix, adnexal lesions, prolapse, intrauterine lesions and coagulation disorders were excluded. By way of preparation, danazol was administered for 4 weeks before the intervention (36 patients). Three patients with side effects were given lynestrenol. From January 1992, an LH-RH analogue was administered (29 patients) for 6 weeks prior to the intervention or in the patients with a subserous myoma for 12 weeks. Thermodestruction of the endometrium by means of radio waves was carried out according to a standard protocol under general or epidural spinal anaesthesia. The intracavitary temperature measured was 62-65 degrees C, mean duration of the treatment 20 minutes.RESULTS:
The patients were discharged 10-24 hours after the intervention. A non-disturbing watery discharge of 3-6 weeks' duration was reported. Normal activities were resumed after one week. Success (duration of follow-up 3-21 months) was defined as amenorrhoea (6 patients; 9%) or a markedly reduced menstruation or duration of menstruation (48 patients; 70%). Six patients (9%) reported no improvement and of eight patients (12%) with slight, unsatisfactory improvement three were treated again, with success (4%). During the trial period the method was further adjusted and perfected. There were no complications.CONCLUSION:
This preliminary experience shows that thermodestruction with radio waves is simple, safe and efficient.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Diathermy
/
Menorrhagia
Type of study:
Guideline
/
Observational_studies
/
Prognostic_studies
Limits:
Adult
/
Female
/
Humans
/
Middle aged
Language:
Nl
Journal:
Ned Tijdschr Geneeskd
Year:
1993
Type:
Article