Degradation pathways for recombinant human macrophage colony-stimulating factor in aqueous solution.

Schrier, J A; Kenley, R A; Williams, R; Corcoran, R J; Kim, Y; Northey, R P; D'Augusta, D; Huberty, M

Schrier, J A; Kenley, R A; Williams, R; Corcoran, R J; Kim, Y; Northey, R P; D'Augusta, D; Huberty, M.

Affiliation

Schrier JA; Genetics Institute, Andover, Massachusetts 01810.

Pharm Res ; 10(7): 933-44, 1993 Jul.

Article in En | MEDLINE | ID: mdl-8378255

Subject(s)

Macrophage Colony-Stimulating Factor/chemistry; Alcaligenes/metabolism; Amino Acid Sequence; Animals; Bone Marrow/drug effects; Bone Marrow Cells; CHO Cells; Calorimetry, Differential Scanning; Chromatography, Gel; Chromatography, High Pressure Liquid; Cricetinae; Electrophoresis, Polyacrylamide Gel; Humans; Hydrogen-Ion Concentration; Kinetics; Mice; Molecular Sequence Data; Peptide Mapping; Protein Denaturation; Receptor, Macrophage Colony-Stimulating Factor; Recombinant Proteins/chemistry; Solutions; Spectrometry, Mass, Fast Atom Bombardment

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Collection: 01-internacional Database: MEDLINE Main subject: Macrophage Colony-Stimulating Factor Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Pharm Res Year: 1993 Type: Article

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