The Fli-1 proto-oncogene, involved in erythroleukemia and Ewing's sarcoma, encodes a transcriptional activator with DNA-binding specificities distinct from other Ets family members.

Zhang, L; Lemarchandel, V; Romeo, P H; Ben-David, Y; Greer, P; Bernstein, A

Zhang, L; Lemarchandel, V; Romeo, P H; Ben-David, Y; Greer, P; Bernstein, A.

Affiliation

Zhang L; Division of Molecular and Developmental Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.

Oncogene ; 8(6): 1621-30, 1993 Jun.

Article in En | MEDLINE | ID: mdl-8502483

Subject(s)

DNA-Binding Proteins/genetics; Friend murine leukemia virus/genetics; Leukemia, Erythroblastic, Acute/genetics; Proto-Oncogene Proteins/genetics; Proto-Oncogene Proteins/metabolism; Proto-Oncogenes; Sarcoma, Ewing/genetics; Spleen Focus-Forming Viruses/genetics; Trans-Activators/genetics; Transcription Factors/genetics; Animals; Base Sequence; Cell Line; DNA-Binding Proteins/metabolism; Humans; Leukemia, Experimental/genetics; Leukemia, Experimental/microbiology; Mice; Molecular Sequence Data; Oligodeoxyribonucleotides; Platelet Membrane Glycoproteins/genetics; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Protein c-fli-1; Proto-Oncogene Proteins c-ets; Sequence Homology, Nucleic Acid; Trans-Activators/metabolism; Transcription Factors/metabolism; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Sarcoma, Ewing / Transcription Factors / Spleen Focus-Forming Viruses / Proto-Oncogenes / Leukemia, Erythroblastic, Acute / Trans-Activators / Proto-Oncogene Proteins / DNA-Binding Proteins / Friend murine leukemia virus Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 1993 Type: Article Affiliation country: Canada

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