X-ray structure of a hydroxamate inhibitor complex of stromelysin catalytic domain and its comparison with members of the zinc metalloproteinase superfamily.

Dhanaraj, V; Ye, Q Z; Johnson, L L; Hupe, D J; Ortwine, D F; Dunbar, J B; Rubin, J R; Pavlovsky, A; Humblet, C; Blundell, T L

Dhanaraj, V; Ye, Q Z; Johnson, L L; Hupe, D J; Ortwine, D F; Dunbar, J B; Rubin, J R; Pavlovsky, A; Humblet, C; Blundell, T L.

Affiliation

Dhanaraj V; Department of Crystallography, Birkbeck College, London, UK.

Structure ; 4(4): 375-86, 1996 Apr 15.

Article in En | MEDLINE | ID: mdl-8740360

Subject(s)

Enzyme Inhibitors/chemistry; Matrix Metalloproteinase 3/chemistry; Matrix Metalloproteinase Inhibitors; Amino Acid Sequence; Binding Sites; Collagenases/chemistry; Crystallography, X-Ray; Enzyme Inhibitors/metabolism; Hydroxamic Acids/chemistry; Magnetic Resonance Spectroscopy; Matrix Metalloproteinase 3/metabolism; Metalloendopeptidases/chemistry; Models, Molecular; Molecular Sequence Data; Protein Conformation; Sequence Homology, Amino Acid; Zinc/chemistry; Zinc/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Matrix Metalloproteinase 3 / Enzyme Inhibitors / Matrix Metalloproteinase Inhibitors Language: En Journal: Structure Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA / BIOTECNOLOGIA Year: 1996 Type: Article Affiliation country: United kingdom

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