[Can the extent of glaucoma damage be quantified with laser polarimetry by in vivo measurement of retinal nerve fiber density? A clinical study]. / Lässt sich mittels Laserpolarimetrie durch In-vivo-Messung der retinalen Nervenfaserschichtdicke das Ausmass des Glaukomschadens quantifizieren? Eine Klinische Studie.

ABSTRACT

Thirty-eight eyes of 38 glaucoma patients with a defined up-down asymmetry of visual field loss (VFL) were examined to ascertain whether there was corresponding up-down asymmetry of nerve fiber layer thickness (NFLT), calculated by laser polarimetry (LP). The correspondence was found to be closer for small up-down asymmetry of VFL then for medium or large up-down asymmetry. An approximately 6% greater NFLT in the lower than in the upper retinal half was revealed found by examination of 62 eyes of 62 normals. Considering this NFLT asymmetry in normals, there was a non-significant tendency towards correspondence between the up-down asymmetry of VFL and the up-down asymmetry of NFLT for the group of glaucoma patients with large up-down asymmetry of VFL. However, in about 40% of cases there was no such correspondence, so that staging of the glaucomatous disease has to be done by perimetry and is not possible by LP (software version 06/93).