Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility.

Danielson, K G; Baribault, H; Holmes, D F; Graham, H; Kadler, K E; Iozzo, R V

Danielson, K G; Baribault, H; Holmes, D F; Graham, H; Kadler, K E; Iozzo, R V.

Affiliation

Danielson KG; Department of Pathology, Anatomy, and Cell Biology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

J Cell Biol ; 136(3): 729-43, 1997 Feb 10.

Article in En | MEDLINE | ID: mdl-9024701

Subject(s)

Collagen/metabolism; Proteoglycans/metabolism; Skin Diseases/metabolism; Animals; Decorin; Extracellular Matrix Proteins; Female; Homozygote; Male; Mice; Mice, Knockout; Proteoglycans/genetics; Skin/metabolism; Skin/pathology; Skin Diseases/genetics; Skin Diseases/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteoglycans / Skin Diseases / Collagen Limits: Animals Language: En Journal: J Cell Biol Year: 1997 Type: Article Affiliation country: United States

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