Evaluation of commercially available assays of neopterin and beta 2-microglobulin for the assessment of disease progression in FIV-infected cats.
Vet Immunol Immunopathol
; 56(1-2): 185-9, 1997 May.
Article
in En
| MEDLINE
| ID: mdl-9220591
ABSTRACT
Serum or plasma samples from cats at different stages of feline immunodeficiency (FIV) infection and from uninfected cats were tested using immunoassays designed to detect human neopterin and beta 2-microglobulin (beta 2M). The results obtained from the anti-human neopterin assay did not correlate with infection status, time post-infection, fCD4 count or clinical picture. Feline samples gave negative results in the anti-human beta 2M assay. The assay kits used in this study are not suitable for the determination of the effect of FIV infection on immune activation markers in the cat.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Reagent Kits, Diagnostic
/
Biopterins
/
Cat Diseases
/
Feline Acquired Immunodeficiency Syndrome
/
Beta 2-Microglobulin
/
Immunodeficiency Virus, Feline
Limits:
Animals
/
Humans
Language:
En
Journal:
Vet Immunol Immunopathol
Year:
1997
Type:
Article
Affiliation country:
United kingdom