[Pancreatic involvement, ascites and diarrhea in idiopathic hypereosinophilic syndrome]. / Atteinte pancréatique, ascite et diarrhée au cours d'un syndrome hyperéosinophilique idiopathique.
Gastroenterol Clin Biol
; 21(6-7): 519-22, 1997.
Article
in Fr
| MEDLINE
| ID: mdl-9295982
ABSTRACT
We report a new case of idiopathic hypereosinophilic syndrome with multivisceral digestive failure. After an erroneous diagnosis of pancreatic cancer, the pathological examination of pancreaticoduodenectomy specimen demonstrated pancreatic fibrosis with eosinophilic infiltration without gastritis or duodenitis. The diagnosis of idiopathic hypereosinophilic syndrome was made three months later upon the classical criteria a) blood eosinophilia of 1.5 G/L or more, persisting for more than 6 months; b) lack of evidence for any other recognised cause of eosinophilia c) multiple organ systemic involvement rheumatologic, cutaneous and digestive (pancreatitis, ascites and diarrhoea) d) previous history of allergic disease and increased plasmatic IgE levels; e) absence of leukemic markers. This case emphasises the difficulty in classifying eosinophilic infiltration of the gut and the possibility of transitional forms between eosinophilic gastro-enteritis and idiopathic hypereosinophilic syndrome. We argue that in case of eosinophilic infiltration of the gut, systematic research of multiple organ systemic involvement is mandatory.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pancreatitis
/
Ascites
/
Hypereosinophilic Syndrome
/
Diarrhea
Type of study:
Diagnostic_studies
Limits:
Aged
/
Female
/
Humans
Language:
Fr
Journal:
Gastroenterol Clin Biol
Year:
1997
Type:
Article