Cytostatic activity of some compounds from the unsaponifiable fraction obtained from virgin olive oil.

Saenz, M T; Garcia, M D; Ahumada, M C; Ruiz, V

Saenz, M T; Garcia, M D; Ahumada, M C; Ruiz, V.

Affiliation

Saenz MT; Laboratori do Farmacognosia, Universidad de Sevilla, 41012 Seville, Spain

Farmaco ; 53(6): 448-9, 1998 Jun 30.

Article in En | MEDLINE | ID: mdl-9786644

ABSTRACT

ABSTRACT

Oleuropein, tyrosol, squalene and the fraction of sterols and triterpenoid dialcohols from the unsaponifiable fraction obtained from virgin olive oil have been tested for possible cytostatic activity against McCoy cells, using 6-mercaptopurine as a positive control. The samples of sterols and triterpenic dialcohols showed a strong activity.

Subject(s)

Antineoplastic Agents, Phytogenic/pharmacology; Plant Oils/chemistry; Antineoplastic Agents, Phytogenic/isolation & purification; Cell Division/drug effects; Cell Line; Humans; Iridoid Glucosides; Iridoids; Olive Oil; Phenylethyl Alcohol/analogs & derivatives; Phenylethyl Alcohol/pharmacology; Pyrans/pharmacology; Squalene/pharmacology; Sterols/pharmacology; Triterpenes/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Plant Oils / Antineoplastic Agents, Phytogenic Limits: Humans Language: En Journal: Farmaco Journal subject: FARMACOLOGIA / QUIMICA Year: 1998 Type: Article Affiliation country: Spain

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