Retention of limulus amoebocyte lysate reactive bacterial products by polysulfone dialyzers is affected by the type of disinfectant.
ASAIO J
; 44(5): M587-91, 1998.
Article
in En
| MEDLINE
| ID: mdl-9804501
ABSTRACT
To reduce the level of contamination by bacterial products, ultrafiltration systems have been introduced and validated for their capacity to block the passage of bacterial components reactive to the limulus amoebocyte lysate (LAL) test. In this study, the absorptive capacity of polysulfone membranes undergoing disinfection cycles with free chlorine and peracetic acid were evaluated at various concentrations and contact times. The results of this study implicate a relevant physicochemical derangement of the polysulfone membranes treated with sodium hypochlorite but not with peracetic acid, diluted peracetic acid (Dialox) or Amuchina. The implications for the practical use of ultrafilters are discussed.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Polymers
/
Sulfones
/
Renal Dialysis
/
Disinfectants
/
Limulus Test
/
Membranes, Artificial
Language:
En
Journal:
ASAIO J
Journal subject:
TRANSPLANTE
Year:
1998
Type:
Article
Affiliation country:
Italy