Identification of activating c-kit mutations in adult-, but not in childhood-onset indolent mastocytosis: a possible explanation for divergent clinical behavior.

Büttner, C; Henz, B M; Welker, P; Sepp, N T; Grabbe, J

Büttner, C; Henz, B M; Welker, P; Sepp, N T; Grabbe, J.

Affiliation

Büttner C; Department of Dermatology, Charité, Humboldt University, Berlin, Germany.

J Invest Dermatol ; 111(6): 1227-31, 1998 Dec.

Article in En | MEDLINE | ID: mdl-9856847

Subject(s)

Age of Onset; Mastocytosis/epidemiology; Mastocytosis/genetics; Proto-Oncogene Proteins c-kit/genetics; Adult; Biopsy; Cell Count; Child; Child, Preschool; Cloning, Molecular; Coloring Agents; Female; Genes; Humans; Infant; Male; Mast Cells/cytology; Middle Aged; Proto-Oncogene Mas; Skin/pathology; Tolonium Chloride; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Mastocytosis / Age of Onset / Proto-Oncogene Proteins c-kit Type of study: Diagnostic_studies / Prognostic_studies Limits: Adult / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Language: En Journal: J Invest Dermatol Year: 1998 Type: Article Affiliation country: Germany

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