Early surgical outcomes of coronary heart disease with severe ischemic mitral regurgitation / 南方医科大学学报
Journal of Southern Medical University
; (12): 1072-1074, 2011.
Article
in Zh
| WPRIM
| ID: wpr-235193
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To summarize the experience with surgical treatment of coronary artery disease with severe ischemic mitral valve regurgitation (IMR).</p><p><b>METHODS</b>From January 2006 to December 2009, 45 patients (35 males, 10 females aged 32-74 years) with the diagnosis of coronary artery disease complicated by IMR underwent coronary artery bypass grafting (CABG) combined with mitral valve plasty (MVP, 24 cases) or mitral valve replacement (MVR, 21 cases).</p><p><b>RESULTS</b>Perioperative deaths occurred in 2 cases due to multiple organ failure (MOF). Echocardiography showed a significant reduction of the mitral regurgitation area (from 11.80∓2.45 cm(2) to 2.83∓0.98 cm(2), t=22.80, P=0.00) after CABG combined with mitral valve surgery, with also significantly reduced postoperative left ventricular end diastolic diameter (LVEDD) (from 57.61∓10.06 mm to 51.84∓8.98 mm, t=2.85, P=0.005). No significant difference was detected in the left ventricular ejection fraction after the operation [(52.7∓15.4)% vs (53.2∓13.2)%, t=0.16, P=0.87)].</p><p><b>CONCLUSIONS</b>CABG combined with mitral valve surgery can improve early postoperative left ventricular function in patients with ischemic coronary heart disease complicated by severe mitral regurgitation, but further follow-up study is still needed for evaluation of the long-term results.</p>
Full text:
1
Database:
WPRIM
Main subject:
General Surgery
/
Coronary Artery Bypass
/
Treatment Outcome
/
Myocardial Ischemia
/
Coronary Disease
/
Mitral Valve Insufficiency
Type of study:
Observational_studies
/
Prognostic_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Zh
Journal:
Journal of Southern Medical University
Year:
2011
Type:
Article