"Evaluation of the ""Multi-Efficacy of One Drug"" of Traditional Chinese medicines Based on the Biological Target Network: Towards Precision Medicine" / 世界科学技术-中医药现代化
World Science and Technology-Modernization of Traditional Chinese Medicine
; (12): 44-49, 2017.
Article
in Zh
| WPRIM
| ID: wpr-673072
Responsible library:
WPRO
ABSTRACT
Multi-Efficacy of One Drug (MEOD) refers to the traditional Chinese medicines (TCM) with diverse efficacies.MEOD,one of the important characteristics of TCM,is regarded as the basis of clinical rational drug use.However,there have been few reports on the MEOD research so far.In this paper,with rhubarb selected as a typical model drug,metabolomics and network pharmacology analysis are integrated to investigate the mechanisms of MEOD with the employment of the two animal models of constipation and jaundice.Then,the biological target network of MEOD is established for promoting the precision of the quality control and clinical use of TCM.
Full text:
1
Database:
WPRIM
Type of study:
Prognostic_studies
Language:
Zh
Journal:
World Science and Technology-Modernization of Traditional Chinese Medicine
Year:
2017
Type:
Article