Anti-inflammatory Action of Yangfeihuoxue Decoction and Its Effects on Inflammatory Mediums in Blood of Rat with Pulmonary Fibrosis / 中成药

ABSTRACT

Objective:To observe the anti inflammatory action of Yangfeihuoxue Decoction and its effects on inflammatory mediums. Methods: The mouse and rat inflammatory models were established by dimethylbenzene, carrageenin and paper strip investing method, and the rat model of pulmonary fibrosis was established by bleomycin. The inhibition of Yangfeihuoxue Decoction on various inflammatory reactions (with swelling rate, swelling degree and height of granuloma as markers) and its effects on levels of histamine (H) and tumor necrosis factor (TNF) in blood were studied. Results: Yanfeihuoxue Decoction can obviously inhibit acute, subacute and chronic inflammatory disease ( P