A Cross-sectional Survey Assessing Carriage of Streptococcus pneumoniae in a Healthy Population in Xinjiang Uygur Autonomous Region of China / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
; (12): 233-237, 2018.
Article
in En
| WPRIM
| ID: wpr-690666
Responsible library:
WPRO
ABSTRACT
The carriage rate and serotype distribution of Streptococcus pneumoniae (S. pneumoniae) in a healthy population in China remains unclear. In this study, we collected the oropharyngeal swabs from 513 individuals in Xinjiang, China. Real-time PCR targeting the lytA gene and 12 serotypes were assessed to identify S. pneumoniae carriage. The total carriage rate of S. pneumoniae was 70.4% (361/513). The most prevalent serotypes were 19B/F, 18B/C, 5, and 6A/B. The highest carriage rate of S. pneumoniae was noted in children aged 6-10 years (88.6%), which merits further attention. The co-colonization rate of two or more S. pneumoniae serotypes was 79.8% (264/331). This study aimed to investigate the baseline pneumococcal carriage rate among healthy individuals in China to improve our understanding of the epidemiology of S. pneumoniae.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Pneumococcal Infections
/
Streptococcus pneumoniae
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Carrier State
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China
/
Epidemiology
/
Prevalence
/
Cross-Sectional Studies
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Classification
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Real-Time Polymerase Chain Reaction
/
Serogroup
Type of study:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Adolescent
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Adult
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Child
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Child, preschool
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Female
/
Humans
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Infant
/
Male
Country/Region as subject:
Asia
Language:
En
Journal:
Biomedical and Environmental Sciences
Year:
2018
Type:
Article