Immune responses to adenoviruses: viral evasion mechanisms and their implications for the clinic.
Curr Opin Immunol
; 11(4): 380-6, 1999 Aug.
Article
en En
| MEDLINE
| ID: mdl-10448144
ABSTRACT
Adenoviruses encode proteins that block responses to interferons, intrinsic cellular apoptosis, killing by CD8(+) cytotoxic T lymphocytes and killing by the death ligands TNF, Fas ligand and TRAIL. The viral proteins are believed to prolong acute and persistent adenovirus infections. The proteins may prove useful in protecting adenovirus gene therapy vectors and transplanted cells from the immune system.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Adenoviridae
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Curr Opin Immunol
Asunto de la revista:
ALERGIA E IMUNOLOGIA
Año:
1999
Tipo del documento:
Article
País de afiliación:
Estados Unidos