Treatment of membranous Budd-Chiari syndrome: analysis of 480 cases.

ABSTRACT

BACKGROUND: Budd-Chiari syndrome (BCS) presents a kind of disease resulted from the occlusion of hepatic vein and/or the intrahepatic inferior vena cava. Its different pathological types were proposed. According to our experience, the membranous type takes a large part of it, and we tried to explore the best treatment of membranous BCS through the analysis of 480 cases retrospectively. METHOD: The operative results of 480 patients with membranous BCS were analysed retrospectively. RESULTS: Patients after Kimura's finger rupture, interventional treatment and membrane resection were followed up with rates of 84.62%, 86.55%, and 87.37%, respectively. The effective rates of the three methods were 61.4%, 91.7%, and 90.4%, respectively, and the recurrence rates of the disease after the 3 procedures were 38.6%, 8.3% and 9.6%, respectively. The long-term effects of interventional treatment and resection were significantly better than those of Kimura's finger rupture (P<0.05). CONCLUSION: Balloon dilatation is the choice for membranous BCS. Patients with extensive lesion, thick membrane or recurrence after percutaneous transhepatic angiography should undergo membrane resection.