Differential pulse, square wave and adsorptive stripping voltammetric quantification of tianeptine in tablets.
J Pharm Biomed Anal
; 41(4): 1157-63, 2006 Jun 16.
Article
en En
| MEDLINE
| ID: mdl-16597493
ABSTRACT
Differential pulse polarographic (DPP) and square wave polarographic (SWP) techniques were applied at hanging mercury drop electrode (HMDE) for quantitative determination of tianeptine (TIA) in tablets. The adsorptive stripping voltammetric (ASV) behavior of TIA was also studied. TIA gave a sensitive reduction peaks at -1256, -1244 and -1072 mV for DPP, SWP and ASV, respectively (versus Ag/AgCl) in Britton-Robinson buffer (B-R buffer) at pH 11. The solution conditions and instrumental parameters were optimized for the determination of TIA in tablets. Calibration plots and regression data validation, accuracy, precision, limit of detection, limit of quantitation and other aspects of analytical merit are presented.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Polarografía
/
Tiazepinas
/
Antidepresivos Tricíclicos
Idioma:
En
Revista:
J Pharm Biomed Anal
Año:
2006
Tipo del documento:
Article
País de afiliación:
Egipto