Parenteral lorazepam versus parenteral haloperidol for the control of psychotic disruptive behavior.
J Clin Psychiatry
; 52(4): 177-80, 1991 Apr.
Article
en En
| MEDLINE
| ID: mdl-1673123
ABSTRACT
In a double-blind, prospective study, 2 mg of intramuscular lorazepam and 5 mg of intramuscular haloperidol were equally effective in controlling aggression, agitation, and assaultive behavior. Although lorazepam and haloperidol produced an equivalent mean decrease in aggression, significantly more subjects who received lorazepam had a greater decrease in aggression ratings than haloperidol recipients; this effect was independent of sedation. Lorazepam produced significantly fewer extrapyramidal symptoms. These data support the current clinical practice of using lorazepam (alone, or in combination with a neuroleptic) for control of acute aggressive and assaultive behavior.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Trastornos Psicóticos
/
Agresión
/
Haloperidol
/
Lorazepam
Tipo de estudio:
Clinical_trials
/
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Humans
Idioma:
En
Revista:
J Clin Psychiatry
Año:
1991
Tipo del documento:
Article