[The clinical features and outcomes of immunoglobulin light-chain amyloidosis with heart involvement].
Zhonghua Xin Xue Guan Bing Za Zhi
; 35(4): 340-3, 2007 Apr.
Article
en Zh
| MEDLINE
| ID: mdl-17711661
ABSTRACT
OBJECTIVE:
To analyze the clinical features and outcomes of patients with immunoglobulin light-chain amyloidosis (AL) who had heart involvement.METHODS:
Clinical features and outcomes of AL amyloidosis patients with heart involvement in the past 7 years in our hospital were retrospectively analyzed.RESULTS:
Cardiac involvement was seen in 36 out of the 60 AL patients (60%). The clinical manifestations of cardiac amyloidosis included heart failure (50%), low QRS voltage (47.2%) and pseudomyocardial infarction (33.3%) in electrocardiography, as well as thickening of ventricular wall (63.9%), echo of granular sparkling texture (11.1%), atria dilation (33.3%) and diastolic dysfunction (30.6%) in echocardiography. The prognosis was poor, with a median survival time of 13.9 months.CONCLUSION:
Patients of AL amyloidosis with cardiac involvement are not rare. Thickening of ventricular wall and diastolic dysfunction are the most common characteristics. Special attention should be paid to this disease.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Amiloidosis
/
Cardiomiopatías
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Límite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Revista:
Zhonghua Xin Xue Guan Bing Za Zhi
Año:
2007
Tipo del documento:
Article
País de afiliación:
China