Ion-specific effects on the interaction between fibronectin and negatively charged mica surfaces.
Langmuir
; 26(8): 5304-8, 2010 Apr 20.
Article
en En
| MEDLINE
| ID: mdl-20345156
ABSTRACT
Atomic force microscopy (AFM) imaging and subsequent image analysis have been used to measure the ion-specific and ionic strength effects on the adsorption of fibronectin to mica surfaces in buffer solution. Increasing the concentration of monovalent Na(+) salt solutions is shown to cause a transition from tightly aggregated and "string-of-beads" structures on the mica surface to well dispersed single-molecule adsorption. Studying the effect of two divalent salts, Ni(2+) and Ca(2+), reveals a dramatic enhancement of fibronectin adsorption to mica in buffer solutions containing Ni(2+), but not for Ca(2+). The origin of this ion-specific effect is discussed.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Fibronectinas
/
Silicatos de Aluminio
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Langmuir
Asunto de la revista:
QUIMICA
Año:
2010
Tipo del documento:
Article
País de afiliación:
Reino Unido