Euchromatic 16p+ heteromorphism: first report in North America.
Am J Med Genet
; 37(4): 548-50, 1990 Dec.
Article
en En
| MEDLINE
| ID: mdl-2260607
ABSTRACT
A heteromorphism of the short arm of 16 (16p+) was discovered in 2 unrelated infants. By G banding, the euchromatic variant appears as a light and a medium dark band just distal to the centromere. This results in an increase of the short arm by about 1/3. The same variant was present in the normal father and the normal paternal grandmother in one family and mildly retarded mother in the 2nd family. The anomalies of the 2 infants are not similar and are apparently unrelated to the 16p+ variant. Though the discovery of such euchromatic variants is highly significant for clinical diagnosis, their genetic significance and mode of origin remain to be elucidated.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Variación Genética
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Anomalías Múltiples
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Cromosomas Humanos Par 16
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Aberraciones Cromosómicas
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Cara
Límite:
Humans
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Infant
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Male
Idioma:
En
Revista:
Am J Med Genet
Año:
1990
Tipo del documento:
Article