Internet-based self-help treatment for depression in multiple sclerosis: study protocol of a randomized controlled trial.
BMC Psychiatry
; 12: 137, 2012 Sep 11.
Article
en En
| MEDLINE
| ID: mdl-22967202
ABSTRACT
BACKGROUND:
Depression in MS patients is frequent but often not treated adequately. An important underlying factor may be physical limitations that preclude face-to-face contact. Internet-based treatment showed to be effective for depressive symptoms in general and could thus be a promising tool for treatment in MS. METHODS/DESIGN:
Here, we present a study protocol to investigate the effectiveness of a 5 week Internet-based self-help problem solving treatment (PST) for depressive symptoms in MS patients in a randomized controlled trial. We aim to include 166 MS patients with moderate to severe depressive symptoms who will be randomly assigned to an Internet-based intervention (with or without supportive text-messages) or waiting list control group. The primary outcome is the change in depressive symptoms defined by a change in the sum score on the Beck Depression Inventory (BDI-II). Secondary outcomes will include measures of anxiety, fatigue, cognitive functioning, physical and psychological impact of MS, quality of life, problem solving skills, social support, mastery, satisfaction and compliance rate. Assessments will take place at baseline (T0), within a week after the intervention (T1), at four months (T2) and at ten months follow-up (T3 only the intervention group). The control group will be measured at the same moments in time. Analysis will be based on the intention-to-treat principle.DISCUSSION:
If shown to be effective, Internet-based PST will offer new possibilities to reach and treat MS patients with depressive symptoms and to improve the quality of care. TRIAL REGISTRATION The Dutch Cochrane Center, NTR2772.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Psicoterapia
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Terapia Asistida por Computador
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Consulta Remota
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Trastorno Depresivo
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Esclerosis Múltiple
Tipo de estudio:
Clinical_trials
/
Guideline
/
Qualitative_research
Límite:
Female
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Humans
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Male
Idioma:
En
Revista:
BMC Psychiatry
Asunto de la revista:
PSIQUIATRIA
Año:
2012
Tipo del documento:
Article
País de afiliación:
Países Bajos