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Host-pathogen interactions in streptococcal immune sequelae.
Nitsche-Schmitz, D Patric; Chhatwal, Gursharan S.
Afiliación
  • Nitsche-Schmitz DP; Helmholtz Centre for Infection Research, Inhoffenstraße 7, D-38124 Braunschweig, Germany. Patric.Nitsche@helmholtz-hzi.de
Curr Top Microbiol Immunol ; 368: 155-71, 2013.
Article en En | MEDLINE | ID: mdl-23212184
Otherwise uncomplicated infections with Streptococcus pyogenes can cause two insidious immune sequelae known as post-streptococcal glomerulonephritis (PSGN) and acute rheumatic fever (ARF). These diseases follow with a latency of a few weeks or months after primary infection and are responsible for high mortality and morbidity. PSGN has also been linked to infections with group C streptococci of the species S. equi ssp. zooepidemicus (SESZ). Moreover, there are some indications that infection with group C and G streptococci (GCGS) of the subspecies Streptococcus dysgalactiae ssp. equisimilis (SDSE) leads to ARF. Despite decades of research, the picture of the molecular pathogenesis of streptococcal immune sequelae resembles a jigsaw puzzle. Herein we try to put some of the puzzle bits together that have been collected till date.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones Estreptocócicas / Streptococcus / Interacciones Huésped-Patógeno Tipo de estudio: Etiology_studies Límite: Animals / Humans Idioma: En Revista: Curr Top Microbiol Immunol Año: 2013 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones Estreptocócicas / Streptococcus / Interacciones Huésped-Patógeno Tipo de estudio: Etiology_studies Límite: Animals / Humans Idioma: En Revista: Curr Top Microbiol Immunol Año: 2013 Tipo del documento: Article País de afiliación: Alemania