In vivo MRI cell tracking using perfluorocarbon probes and fluorine-19 detection.
NMR Biomed
; 26(7): 860-71, 2013 Jul.
Article
en En
| MEDLINE
| ID: mdl-23606473
ABSTRACT
This article presents a brief review of preclinical in vivo cell-tracking methods and applications using perfluorocarbon (PFC) probes and fluorine-19 ((19) F) MRI detection. Detection of the (19) F signal offers high cell specificity and quantification ability in spin density-weighted MR images. We discuss the compositions of matter, methods and applications of PFC-based cell tracking using ex vivo and in situ PFC labeling in preclinical studies of inflammation and cellular therapeutics. We also address the potential applicability of (19) F cell tracking to clinical trials.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Imagen por Resonancia Magnética
/
Sondas Moleculares
/
Rastreo Celular
/
Flúor
/
Fluorocarburos
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
NMR Biomed
Asunto de la revista:
DIAGNOSTICO POR IMAGEM
/
MEDICINA NUCLEAR
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos