Rituximab therapy for refractory idiopathic scleritis.
Ocul Immunol Inflamm
; 21(4): 329-32, 2013 Aug.
Article
en En
| MEDLINE
| ID: mdl-23662782
ABSTRACT
PURPOSE:
To report 2 cases of refractory idiopathic scleritis treated with rituximab.DESIGN:
Interventional case series. METHODS ANDRESULTS:
Case 1 A 54-year-old woman, presented with anterior idiopathic scleritis in her right eye. Treatment with systemic steroids was not effective. Intravenous cyclophosphamide was discontinued after an adverse event. Case 2 A 43-year-old woman presented with idiopathic posterior scleritis in her left eye. Initial treatment with steroids was ineffective. In both cases, long-lasting remission without further relapses was achieved after 4 weekly doses (375 mg/m(2)) of rituximab.CONCLUSION:
Rituximab was found to be an effective treatment for refractory idiopathic anterior and posterior scleritis.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Escleritis
/
Anticuerpos Monoclonales de Origen Murino
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Límite:
Adult
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Ocul Immunol Inflamm
Asunto de la revista:
ALERGIA E IMUNOLOGIA
/
OFTALMOLOGIA
Año:
2013
Tipo del documento:
Article