Adenina/farmacología; Receptores Purinérgicos P2X3/metabolismo; Adenina/análogos & derivados; Adenina/química; Animales; Relación Dosis-Respuesta a Droga; Células HEK293; Humanos; Ratones; Modelos Moleculares; Estructura Molecular; Ratas; Proteínas Recombinantes/metabolismo; Relación Estructura-Actividad

2',3'-O-(2,4,6-trinitrophenyl)-ATP; ATP; Adenine derivatives; CPU; DCM; DRG; HTS; Hill coefficient; MOE; Molecular Operating Environment; NOE; P2X3 receptor; P2X3 receptor antagonists; PPADS; PPP; PTLC; PTSA; Patch clamp; Purine; Purine derivatives; Purinergic receptors; TBAN; TEA; TFAA; TG; TLC; TNP-ATP; central processing unit; dichloromethane; dorsal root ganglion; high-throughput screening; n(H); nuclear Overhauser effect; p-toluenesulfonic acid; preparative thin-layer chromatography; pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid; rise time; tetrabutylammonium nitrate; thin-layer chromatography; time constant of desensitization decay; triethylamine; trifluoroacetic anhydride; trigeminal ganglia; triphosphate; α,ß-meATP; α,ß-methyleneATP; τ(des1;2); τ(on)